zedie posted: " Abstract Inactivation of the most important tumour suppressor gene TP53 occurs in most, if not all, human cancers. Loss of functional wild-type p53 is achieved via two main mechanisms: mutation of the gene leading to an absence of tumour sup" Read on blog or Reader SOMEONE SOMEWHERE Read on blog or Reader Translating p53-based therapies for cancer into the clinic zedie February 29 Abstract Inactivation of the most important tumour suppressor gene TP53 occurs in most, if not all, human cancers. Loss of functional wild-type p53 is achieved via two main mechanisms: mutation of the gene leading to an absence of tumour suppressor activity and, in some cases, gain-of-oncogenic function; or inhibition of the wild-type p53 protein mediated by overexpression […] Read more of this post Comment Like You can also reply to this email to leave a comment.

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